Y29C (p.Tyr29Cys) variant of IFNAR2 (Interferon alpha/beta receptor 2)
Y29C (p.Tyr29Cys) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data, published literature, and structural context.
Y29C (p.Tyr29Cys) variant details
- p.Tyr29Cys
- gnomAD 21-33243703-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0495
- REVEL 0.05
- CADD 0.02
- PolyPhen-2 0.00
- SIFT 0.15
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available
- Literature evidence available