V19L (p.Val19Leu) variant of IFNAR2 (Interferon alpha/beta receptor 2)
V19L (p.Val19Leu) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
V19L (p.Val19Leu) variant details
- p.Val19Leu
- gnomAD rs1170127205
- Missense
- Variant Prioritization Score for Impact Estimate 0.582
- REVEL 0.48
- CADD 33.00
- PolyPhen-2 0.97
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available