T35S (p.Thr35Ser) variant of IFNAR2 (Interferon alpha/beta receptor 2)
T35S (p.Thr35Ser) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data and structural context.
T35S (p.Thr35Ser) variant details
- p.Thr35Ser
- ExAC rs750091350
- TOPMed rs750091350
- Missense
- Variant Prioritization Score for Impact Estimate 0.0351
- REVEL 0.00
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available