S38C (p.Ser38Cys) variant of IFNAR2 (Interferon alpha/beta receptor 2)
S38C (p.Ser38Cys) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
S38C (p.Ser38Cys) variant details
- p.Ser38Cys
- ExAC rs767982536
- TOPMed rs767982536
- gnomAD rs767982536
- Missense
- Variant Prioritization Score for Impact Estimate 0.131
- REVEL 0.09
- CADD 14.40
- PolyPhen-2 0.76
- SIFT 0.18
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available