S28L (p.Ser28Leu) variant of IFNAR2 (Interferon alpha/beta receptor 2)
S28L (p.Ser28Leu) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
S28L (p.Ser28Leu) variant details
- p.Ser28Leu
- gnomAD rs1490350098
- Missense
- Variant Prioritization Score for Impact Estimate 0.179
- REVEL 0.08
- CADD 14.90
- PolyPhen-2 0.04
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available