S22N (p.Ser22Asn) variant of IFNAR2 (Interferon alpha/beta receptor 2)
S22N (p.Ser22Asn) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
S22N (p.Ser22Asn) variant details
- p.Ser22Asn
- gnomAD 21-33243682-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.362
- REVEL 0.33
- CADD 18.00
- PolyPhen-2 0.91
- SIFT 0.16
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available
- Literature evidence available