N6S (p.Asn6Ser) variant of IFNAR2 (Interferon alpha/beta receptor 2)
N6S (p.Asn6Ser) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
N6S (p.Asn6Ser) variant details
- p.Asn6Ser
- TOPMed rs1986964409
- Missense
- Variant Prioritization Score for Impact Estimate 0.0551
- REVEL 0.03
- CADD 3.48
- PolyPhen-2 0.01
- SIFT 0.38
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available