M18L (p.Met18Leu) variant of IFNAR2 (Interferon alpha/beta receptor 2)
M18L (p.Met18Leu) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
M18L (p.Met18Leu) variant details
- p.Met18Leu
- ExAC rs777547168
- gnomAD rs777547168
- Missense
- Variant Prioritization Score for Impact Estimate 0.0778
- REVEL 0.09
- CADD 0.07
- PolyPhen-2 0.00
- SIFT 0.61
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available