L3S (p.Leu3Ser) variant of IFNAR2 (Interferon alpha/beta receptor 2)
L3S (p.Leu3Ser) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
L3S (p.Leu3Ser) variant details
- p.Leu3Ser
- ESP rs141164659
- ExAC rs141164659
- TOPMed rs141164659
- gnomAD rs141164659
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.03
- CADD 11.00
- PolyPhen-2 0.09
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available