L2V (p.Leu2Val) variant of IFNAR2 (Interferon alpha/beta receptor 2)
L2V (p.Leu2Val) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
L2V (p.Leu2Val) variant details
- p.Leu2Val
- gnomAD 21-33241926-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0856
- REVEL 0.02
- CADD 5.36
- PolyPhen-2 0.01
- SIFT 0.21
- Population evidence available
- Structural context available
- Literature evidence available