L2I (p.Leu2Ile) variant of IFNAR2 (Interferon alpha/beta receptor 2)
L2I (p.Leu2Ile) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
L2I (p.Leu2Ile) variant details
- p.Leu2Ile
- gnomAD 21-33241926-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.112
- REVEL 0.05
- CADD 7.22
- PolyPhen-2 0.12
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available