L2F (p.Leu2Phe) variant of IFNAR2 (Interferon alpha/beta receptor 2)
L2F (p.Leu2Phe) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
L2F (p.Leu2Phe) variant details
- p.Leu2Phe
- gnomAD 21-33241926-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.108
- REVEL 0.04
- CADD 8.36
- PolyPhen-2 0.03
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available