L23F (p.Leu23Phe) variant of IFNAR2 (Interferon alpha/beta receptor 2)
L23F (p.Leu23Phe) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
L23F (p.Leu23Phe) variant details
- p.Leu23Phe
- gnomAD 21-33243684-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.204
- REVEL 0.12
- CADD 16.60
- PolyPhen-2 0.17
- SIFT 0.04
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available
- Literature evidence available