K57R (p.Lys57Arg) variant of IFNAR2 (Interferon alpha/beta receptor 2)
K57R (p.Lys57Arg) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
K57R (p.Lys57Arg) variant details
- p.Lys57Arg
- TOPMed rs1359940308
- gnomAD rs1359940308
- Missense
- Variant Prioritization Score for Impact Estimate 0.305
- REVEL 0.35
- CADD 22.00
- PolyPhen-2 0.98
- SIFT 0.08
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available