I27T (p.Ile27Thr) variant of IFNAR2 (Interferon alpha/beta receptor 2)
I27T (p.Ile27Thr) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
I27T (p.Ile27Thr) variant details
- p.Ile27Thr
- TOPMed rs1987172547
- Missense
- Variant Prioritization Score for Impact Estimate 0.0994
- REVEL 0.05
- CADD 6.34
- PolyPhen-2 0.01
- SIFT 0.65
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available