I21V (p.Ile21Val) variant of IFNAR2 (Interferon alpha/beta receptor 2)
I21V (p.Ile21Val) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
I21V (p.Ile21Val) variant details
- p.Ile21Val
- TOPMed rs1987169015
- Missense
- Variant Prioritization Score for Impact Estimate 0.064
- REVEL 0.06
- CADD 0.20
- PolyPhen-2 0.14
- SIFT 0.48
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available