G26D (p.Gly26Asp) variant of IFNAR2 (Interferon alpha/beta receptor 2)
G26D (p.Gly26Asp) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
G26D (p.Gly26Asp) variant details
- p.Gly26Asp
- gnomAD 21-33243694-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.243
- REVEL 0.28
- CADD 3.81
- PolyPhen-2 0.25
- SIFT 0.21
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- Literature evidence available