F8L (p.Phe8Leu) variant of IFNAR2 (Interferon alpha/beta receptor 2)
F8L (p.Phe8Leu) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
F8L (p.Phe8Leu) variant details
- p.Phe8Leu
- gnomAD 21-33241944-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0889
- REVEL 0.05
- CADD 6.46
- PolyPhen-2 0.00
- SIFT 0.80
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available