F41L (p.Phe41Leu) variant of IFNAR2 (Interferon alpha/beta receptor 2)
F41L (p.Phe41Leu) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
F41L (p.Phe41Leu) variant details
- p.Phe41Leu
- gnomAD 21-33244976-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.108
- REVEL 0.14
- CADD 0.00
- PolyPhen-2 0.01
- SIFT 0.64
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available