F41C (p.Phe41Cys) variant of IFNAR2 (Interferon alpha/beta receptor 2)
F41C (p.Phe41Cys) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
F41C (p.Phe41Cys) variant details
- p.Phe41Cys
- gnomAD 21-33244975-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.31
- CADD 22.40
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available
- Literature evidence available