F25L (p.Phe25Leu) variant of IFNAR2 (Interferon alpha/beta receptor 2)
F25L (p.Phe25Leu) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
F25L (p.Phe25Leu) variant details
- p.Phe25Leu
- ExAC rs774056629
- TOPMed rs774056629
- gnomAD rs774056629
- Missense
- Variant Prioritization Score for Impact Estimate 0.0819
- REVEL 0.07
- CADD 4.58
- PolyPhen-2 0.08
- SIFT 0.62
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available