F10C (p.Phe10Cys) variant of IFNAR2 (Interferon alpha/beta receptor 2)
F10C (p.Phe10Cys) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
F10C (p.Phe10Cys) variant details
- p.Phe10Cys
- TOPMed rs1340060960
- gnomAD rs1340060960
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.05
- CADD 17.40
- PolyPhen-2 0.13
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available