E55D (p.Glu55Asp) variant of IFNAR2 (Interferon alpha/beta receptor 2)
E55D (p.Glu55Asp) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
E55D (p.Glu55Asp) variant details
- p.Glu55Asp
- gnomAD rs1453614680
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.27
- CADD 21.50
- PolyPhen-2 0.54
- SIFT 0.01
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available