A7T (p.Ala7Thr) variant of IFNAR2 (Interferon alpha/beta receptor 2)
A7T (p.Ala7Thr) in IFNAR2 (Interferon alpha/beta receptor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
A7T (p.Ala7Thr) variant details
- p.Ala7Thr
- gnomAD rs1331375284
- Missense
- Variant Prioritization Score for Impact Estimate 0.251
- REVEL 0.04
- CADD 7.36
- PolyPhen-2 0.06
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available