W49R (p.Trp49Arg) variant of IFNAR1 (Interferon alpha/beta receptor 1)
W49R (p.Trp49Arg) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data, published literature, and structural context.
W49R (p.Trp49Arg) variant details
- p.Trp49Arg
- gnomAD 21-33335592-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.749
- REVEL 0.79
- MetaLR 0.86
- MetaSVM 0.81
- CADD 25.20
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available