W19L (p.Trp19Leu) variant of IFNAR1 (Interferon alpha/beta receptor 1)
W19L (p.Trp19Leu) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
W19L (p.Trp19Leu) variant details
- p.Trp19Leu
- gnomAD 21-33325111-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.481
- REVEL 0.48
- MetaLR 0.46
- MetaSVM -0.34
- CADD 24.60
- PolyPhen-2 0.77
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available