V56I (p.Val56Ile) variant of IFNAR1 (Interferon alpha/beta receptor 1)
V56I (p.Val56Ile) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
V56I (p.Val56Ile) variant details
- p.Val56Ile
- TOPMed rs1218131188
- gnomAD rs1218131188
- Missense
- Variant Prioritization Score for Impact Estimate 0.0888
- REVEL 0.04
- MetaLR 0.19
- MetaSVM -1.02
- CADD 0.19
- PolyPhen-2 0.01
- SIFT 0.53
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available