V4G (p.Val4Gly) variant of IFNAR1 (Interferon alpha/beta receptor 1)
V4G (p.Val4Gly) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
V4G (p.Val4Gly) variant details
- p.Val4Gly
- gnomAD 21-33325066-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.05
- MetaLR 0.09
- MetaSVM -1.02
- CADD 14.60
- PolyPhen-2 0.00
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available