V36L (p.Val36Leu) variant of IFNAR1 (Interferon alpha/beta receptor 1)
V36L (p.Val36Leu) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
V36L (p.Val36Leu) variant details
- p.Val36Leu
- gnomAD rs2083225754
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.28
- MetaLR 0.35
- MetaSVM -0.66
- CADD 15.10
- PolyPhen-2 0.35
- SIFT 0.71
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available