T9K (p.Thr9Lys) variant of IFNAR1 (Interferon alpha/beta receptor 1)
T9K (p.Thr9Lys) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
T9K (p.Thr9Lys) variant details
- p.Thr9Lys
- gnomAD 21-33325081-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.416
- REVEL 0.19
- MetaLR 0.29
- MetaSVM -0.69
- CADD 22.10
- PolyPhen-2 0.56
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available