T60P (p.Thr60Pro) variant of IFNAR1 (Interferon alpha/beta receptor 1)
T60P (p.Thr60Pro) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
T60P (p.Thr60Pro) variant details
- p.Thr60Pro
- gnomAD 21-33335625-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.587
- REVEL 0.71
- MetaLR 0.57
- MetaSVM 0.08
- CADD 23.10
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available