T10P (p.Thr10Pro) variant of IFNAR1 (Interferon alpha/beta receptor 1)
T10P (p.Thr10Pro) in IFNAR1 (Interferon alpha/beta receptor 1) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data, published literature, and structural context.
T10P (p.Thr10Pro) variant details
- p.Thr10Pro
- rs1409062242
- gnomAD 21-33325081-CG-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.777
- CADD 22.50
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available