S55Y (p.Ser55Tyr) variant of IFNAR1 (Interferon alpha/beta receptor 1)
S55Y (p.Ser55Tyr) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
S55Y (p.Ser55Tyr) variant details
- p.Ser55Tyr
- gnomAD 21-33335611-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.29
- MetaLR 0.42
- MetaSVM -0.71
- CADD 15.40
- PolyPhen-2 0.84
- SIFT 0.40
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available