S55F (p.Ser55Phe) variant of IFNAR1 (Interferon alpha/beta receptor 1)
S55F (p.Ser55Phe) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
S55F (p.Ser55Phe) variant details
- p.Ser55Phe
- ExAC rs757683855
- gnomAD rs757683855
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.14
- MetaLR 0.27
- MetaSVM -0.93
- CADD 7.29
- PolyPhen-2 0.07
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available