S32P (p.Ser32Pro) variant of IFNAR1 (Interferon alpha/beta receptor 1)
S32P (p.Ser32Pro) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
S32P (p.Ser32Pro) variant details
- p.Ser32Pro
- ExAC rs746333531
- gnomAD rs746333531
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.05
- MetaLR 0.16
- MetaSVM -1.01
- CADD 6.55
- PolyPhen-2 0.03
- SIFT 1.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available