S22T (p.Ser22Thr) variant of IFNAR1 (Interferon alpha/beta receptor 1)
S22T (p.Ser22Thr) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
S22T (p.Ser22Thr) variant details
- p.Ser22Thr
- gnomAD 21-33325119-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.194
- REVEL 0.07
- MetaLR 0.23
- MetaSVM -0.81
- CADD 15.30
- PolyPhen-2 0.03
- SIFT 1.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available