R51G (p.Arg51Gly) variant of IFNAR1 (Interferon alpha/beta receptor 1)
R51G (p.Arg51Gly) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
R51G (p.Arg51Gly) variant details
- p.Arg51Gly
- TOPMed rs1354543562
- gnomAD rs1354543562
- Missense
- Variant Prioritization Score for Impact Estimate 0.134
- REVEL 0.14
- MetaLR 0.16
- MetaSVM -0.96
- CADD 0.31
- PolyPhen-2 0.01
- SIFT 0.42
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available