Q34R (p.Gln34Arg) variant of IFNAR1 (Interferon alpha/beta receptor 1)
Q34R (p.Gln34Arg) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
Q34R (p.Gln34Arg) variant details
- p.Gln34Arg
- gnomAD 21-33335548-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.298
- REVEL 0.25
- MetaLR 0.37
- MetaSVM -0.74
- CADD 22.70
- PolyPhen-2 0.84
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available