Q34P (p.Gln34Pro) variant of IFNAR1 (Interferon alpha/beta receptor 1)
Q34P (p.Gln34Pro) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
Q34P (p.Gln34Pro) variant details
- p.Gln34Pro
- ExAC rs775701968
- TOPMed rs775701968
- gnomAD rs775701968
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.29
- MetaLR 0.47
- MetaSVM -0.63
- CADD 22.90
- PolyPhen-2 0.93
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.7e-05)
- Structural context available