P33S (p.Pro33Ser) variant of IFNAR1 (Interferon alpha/beta receptor 1)
P33S (p.Pro33Ser) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
P33S (p.Pro33Ser) variant details
- p.Pro33Ser
- gnomAD 21-33335544-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.486
- REVEL 0.43
- MetaLR 0.79
- MetaSVM 0.57
- CADD 16.40
- PolyPhen-2 1.00
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available