N58K (p.Asn58Lys) variant of IFNAR1 (Interferon alpha/beta receptor 1)
N58K (p.Asn58Lys) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
N58K (p.Asn58Lys) variant details
- p.Asn58Lys
- gnomAD 21-33335621-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.26
- MetaLR 0.59
- MetaSVM -0.31
- CADD 16.60
- PolyPhen-2 0.97
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available