N58D (p.Asn58Asp) variant of IFNAR1 (Interferon alpha/beta receptor 1)
N58D (p.Asn58Asp) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
N58D (p.Asn58Asp) variant details
- p.Asn58Asp
- TOPMed rs1206797104
- gnomAD rs1206797104
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- REVEL 0.17
- MetaLR 0.37
- MetaSVM -0.81
- CADD 11.30
- PolyPhen-2 0.38
- SIFT 0.37
- Most common in the African/African-American population (allele frequency 3.1e-05)
- Structural context available