M2R (p.Met2Arg) variant of IFNAR1 (Interferon alpha/beta receptor 1)
M2R (p.Met2Arg) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
M2R (p.Met2Arg) variant details
- p.Met2Arg
- gnomAD 21-33325060-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.423
- REVEL 0.33
- MetaLR 0.28
- MetaSVM -0.62
- CADD 25.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available