L5V (p.Leu5Val) variant of IFNAR1 (Interferon alpha/beta receptor 1)
L5V (p.Leu5Val) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
L5V (p.Leu5Val) variant details
- p.Leu5Val
- gnomAD rs1401132041
- Missense
- Variant Prioritization Score for Impact Estimate 0.0961
- REVEL 0.03
- MetaLR 0.14
- MetaSVM -0.98
- CADD 7.75
- SIFT 0.32
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available