L13I (p.Leu13Ile) variant of IFNAR1 (Interferon alpha/beta receptor 1)
L13I (p.Leu13Ile) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
L13I (p.Leu13Ile) variant details
- p.Leu13Ile
- gnomAD 21-33325092-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.368
- REVEL 0.35
- MetaLR 0.43
- MetaSVM -0.55
- CADD 22.90
- PolyPhen-2 0.46
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available