L13F (p.Leu13Phe) variant of IFNAR1 (Interferon alpha/beta receptor 1)
L13F (p.Leu13Phe) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
L13F (p.Leu13Phe) variant details
- p.Leu13Phe
- ExAC rs777682349
- gnomAD rs777682349
- Missense
- Variant Prioritization Score for Impact Estimate 0.437
- REVEL 0.46
- MetaLR 0.58
- MetaSVM -0.39
- CADD 23.50
- PolyPhen-2 0.91
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available