L11I (p.Leu11Ile) variant of IFNAR1 (Interferon alpha/beta receptor 1)
L11I (p.Leu11Ile) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
L11I (p.Leu11Ile) variant details
- p.Leu11Ile
- gnomAD 21-33325086-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.247
- REVEL 0.13
- MetaLR 0.33
- MetaSVM -0.69
- CADD 22.50
- PolyPhen-2 0.59
- SIFT 0.74
- Population evidence available
- Structural context available
- Literature evidence available