K31T (p.Lys31Thr) variant of IFNAR1 (Interferon alpha/beta receptor 1)
K31T (p.Lys31Thr) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
K31T (p.Lys31Thr) variant details
- p.Lys31Thr
- ExAC rs771153007
- TOPMed rs771153007
- gnomAD rs771153007
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.14
- MetaLR 0.36
- MetaSVM -0.87
- CADD 8.42
- PolyPhen-2 0.23
- SIFT 0.09
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available