K28R (p.Lys28Arg) variant of IFNAR1 (Interferon alpha/beta receptor 1)
K28R (p.Lys28Arg) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
K28R (p.Lys28Arg) variant details
- p.Lys28Arg
- gnomAD rs1302842958
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.19
- MetaLR 0.26
- MetaSVM -0.92
- CADD 10.70
- PolyPhen-2 0.42
- SIFT 0.54
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available