I46S (p.Ile46Ser) variant of IFNAR1 (Interferon alpha/beta receptor 1)
I46S (p.Ile46Ser) in IFNAR1 (Interferon alpha/beta receptor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
I46S (p.Ile46Ser) variant details
- p.Ile46Ser
- gnomAD 21-33335584-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.46
- MetaLR 0.40
- MetaSVM -0.68
- CADD 11.90
- PolyPhen-2 0.12
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available